Yes, I've run mine on it for years, but I don't get so much oil or time to make it these days and with the cost of chemicals nowadays its not so much of a saving so buying diesel is sometimes easier. But as long as its good quality bio and meets the European standard for biodiesel which is EN14214 then it will run fine this time of year although you may lose a couple of mpg. Winter running on bio is a different matter however and needs the best oil feedstock(no palm, soya or saturated fats etc) to help with gelling around and below zero freezing, and keeping a sample in a bottle near your van so you can see if its starting to gel before you try and start your van, there are several ways of winterising your bio but the easiest is to just add a small amount of petrol.
I would advise getting a couple of spare fuel filters as bio can flush out any old deposits in the fuel tank and lines and clog the filter, not so much of a problem with regularly used vans, but ones that sit around a lot tend to have more gunk as the additives in diesel drop out.
Check your rubber fuel lines and leak off pipes for condition and monitor them for the first few tankfuls as certain fuel pipes are not bio compatible and can degrade or even melt.
A few years back when it was more popular we created a wiki which you may find useful, there is a forum for it too if you want to ask more questions after reading, you'll see the link in the left navigation panel.
https://biopowered.co.uk/wiki/Vegetable ... iesel_wiki